Endocrine Abstracts

Background: CHF manifestations can be explained by the biologic effects of tumor necrosis factor-alpha (TNF-alpha). Interleukin-10 (IL-10) has potent deactivating properties and is considered a potent anti-inflammatory cytokine that inhibits TNF-alpha production. This study was designed to examine the role of IL-10 in patients with CHF and to test its correlation with pro-inflammatory markers.Methodology: Fifty patients with CHF were studied. Patients we...

Background: Resistin is a recently discovered adipocyte-secreted hormone that links obesity with insulin resistance and/or metabolic and cardiovascular risk. This study was designed to investigate whether serum resistin concentrations constitute a significant coronary risk factor, with a particular focus on diabetes and one of its microvascular complications; nephropathy.Methodology: Serum resistin was measured in 86 overweight patients with acute corona...